I have one login on this system (excluding root which I have enabled), with this install setup so I can work in any and experience much of the same experience on any DE; at least for the stuff that matters to me.
GNOME handles workspaces differently; with one monitor not switching when my others do; that is the most significant difference. Second would be my media keys on my [second] keyboard; LXQt for example has them always control my music player, where GNOME/Xfce will have them control whatever I last used (if I’ve only used a music player there won’t be a difference, but I’ve got vlc running with a paused movie, AND my music playlist in clementine or audacious, the media keys will operate whatever I last used). The media keys I can change; but I opted to leave it default. The workspace differences I could possibly also have worked around, but I’m aware of that & sometimes the GNOME approach does work for me.
I’ll provide some links where I talk about the install on this site
- Xubuntu screenshot thread
- Lubuntu screenshot thread
- On those (Xubuntu anyway) I was asked about the multi-desktop thread, that question & answer can be found here.
On the third link you’ll also see me talking about the dracut versus initramfs issue too that I mentioned earlier.